Title |
Carbon monoxide levels after inhalation from new generation heated tobacco products
|
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Published in |
Respiratory Research, August 2018
|
DOI | 10.1186/s12931-018-0867-z |
Pubmed ID | |
Authors |
Pasquale Caponnetto, Marilena Maglia, Gaetano Prosperini, Barbara Busà, Riccardo Polosa |
Abstract |
Heated tobacco products (HTPs) are new tech devices that release nicotine and other volatile compounds into an inhalable aerosol by heating the tobacco. At their operating temperatures, tobacco combustion is unlikely.The aim of this randomized cross-over study was to measure the exposure levels of the combustion marker, carbon monoxide in the exhaled breath (eCO) of subjects after use of two HTPs and to compare these levels with participants' own brand of cigarettes.A total of 12 healthy smokers who reported smoking ≥10 conventional cigarettes per day for at least 5 years took part in the study. Product administration consisted of a first round of 10 puffs, which was followed by an identical second round after a 5 min pause in between rounds. After obtaining a baseline eCO value, this measure was recorded at 5, 10, 15, 30, and 45 min after the first puff of the first round. In contrast to combustible cigarettes, no eCO elevations were observed in the exhaled breath after use of the HTPs under investigation in any of the study participants. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 3 | 19% |
United States | 2 | 13% |
Netherlands | 2 | 13% |
Spain | 2 | 13% |
Finland | 1 | 6% |
Switzerland | 1 | 6% |
Portugal | 1 | 6% |
Canada | 1 | 6% |
Unknown | 3 | 19% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 12 | 75% |
Scientists | 2 | 13% |
Practitioners (doctors, other healthcare professionals) | 1 | 6% |
Science communicators (journalists, bloggers, editors) | 1 | 6% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 50 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 10 | 20% |
Researcher | 6 | 12% |
Student > Ph. D. Student | 4 | 8% |
Student > Master | 4 | 8% |
Student > Doctoral Student | 3 | 6% |
Other | 5 | 10% |
Unknown | 18 | 36% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 10 | 20% |
Nursing and Health Professions | 4 | 8% |
Unspecified | 2 | 4% |
Biochemistry, Genetics and Molecular Biology | 2 | 4% |
Psychology | 2 | 4% |
Other | 8 | 16% |
Unknown | 22 | 44% |