Title |
Update on the third international stroke trial (IST-3) of thrombolysis for acute ischaemic stroke and baseline features of the 3035 patients recruited
|
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Published in |
Trials, November 2011
|
DOI | 10.1186/1745-6215-12-252 |
Pubmed ID | |
Authors |
Peter Sandercock, Richard Lindley, Joanna Wardlaw, Martin Dennis, Karen Innes, Geoff Cohen, Will Whiteley, David Perry, Vera Soosay, David Buchanan, Graham Venables, Anna Czlonkowska, Adam Kobayashi, Eivind Berge, Karsten Bruins Slot, Veronica Murray, Andre Peeters, Graeme J Hankey, Karl Matz, Michael Brainin, Stefano Ricci, Teresa A Cantisani, Gordon Gubitz, Stephen J Phillips, Arauz Antonio, Manuel Correia, Phillippe Lyrer, Ingrid Kane, Erik Lundstrom, the IST-3 collaborative group |
Abstract |
Intravenous recombinant tissue plasminogen activator (rtPA) is approved in Europe for use in patients with acute ischaemic stroke who meet strictly defined criteria. IST-3 sought to improve the external validity and precision of the estimates of the overall treatment effects (efficacy and safety) of rtPA in acute ischaemic stroke, and to determine whether a wider range of patients might benefit. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 40% |
Mexico | 1 | 20% |
Canada | 1 | 20% |
Unknown | 1 | 20% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 5 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 3 | 3% |
Poland | 1 | <1% |
South Africa | 1 | <1% |
Switzerland | 1 | <1% |
Unknown | 96 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 18 | 18% |
Other | 11 | 11% |
Student > Ph. D. Student | 11 | 11% |
Student > Bachelor | 11 | 11% |
Student > Postgraduate | 11 | 11% |
Other | 25 | 25% |
Unknown | 15 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 53 | 52% |
Biochemistry, Genetics and Molecular Biology | 5 | 5% |
Neuroscience | 5 | 5% |
Agricultural and Biological Sciences | 5 | 5% |
Nursing and Health Professions | 3 | 3% |
Other | 11 | 11% |
Unknown | 20 | 20% |