Title |
Soft tissue regeneration using leukocyte-platelet rich fibrin after exeresis of hyperplastic gingival lesions: two case reports
|
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Published in |
Journal of Medical Case Reports, November 2015
|
DOI | 10.1186/s13256-015-0714-5 |
Pubmed ID | |
Authors |
A.E. di Lauro, D. Abbate, B. Dell’Angelo, G.A. Iannaccone, F. Scotto, G. Sammartino |
Abstract |
Leukocyte-platelet rich fibrin belongs to a second generation of platelet concentrates that does not need biochemical blood manipulation. It is used for tissue healing and regeneration in periodontal and oral-maxillofacial surgery. We report two cases of hyperplastic gingival lesions treated by exeresis and application of leukocyte-platelet rich fibrin membranes in order to improve and accelerate tissue healing. Two patients (a 78-year-old Caucasian woman and a 30-year-old Caucasian man) were treated for hyperplastic gingival lesions. They underwent to exeresis of lesions and application of leukocyte-platelet rich fibrin membranes. Tissue healing was clinically evaluated after 1, 3, 7, 14 and 30 postoperative days. No recurrences were observed after 2 years of semi-annual follow up. We obtained rapid and good healing of soft tissues probably due to the elevated content of leukocytes, platelets and growth factors in the leukocyte-platelet rich fibrin. Based on our results we suggest the use of leukocyte-platelet rich fibrin to cover wounds after exeresis of oral neoformations such as hyperplastic gingival lesions. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Brazil | 1 | 2% |
Unknown | 50 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 8 | 16% |
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Professor > Associate Professor | 3 | 6% |
Other | 8 | 16% |
Unknown | 13 | 25% |
Readers by discipline | Count | As % |
---|---|---|
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Chemistry | 1 | 2% |
Other | 0 | 0% |
Unknown | 14 | 27% |