Title |
Model-based clustering reveals vitamin D dependent multi-centrality hubs in a network of vitamin-related proteins
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Published in |
BMC Systems Biology, December 2011
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DOI | 10.1186/1752-0509-5-195 |
Pubmed ID | |
Authors |
Thanh-Phuong Nguyen, Marco Scotti, Melissa J Morine, Corrado Priami |
Abstract |
Nutritional systems biology offers the potential for comprehensive predictions that account for all metabolic changes with the intricate biological organization and the multitudinous interactions between the cellular proteins. Protein-protein interaction (PPI) networks can be used for an integrative description of molecular processes. Although widely adopted in nutritional systems biology, these networks typically encompass a single category of functional interaction (i.e., metabolic, regulatory or signaling) or nutrient. Incorporating multiple nutrients and functional interaction categories under an integrated framework represents an informative approach for gaining system level insight on nutrient metabolism. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Italy | 4 | 9% |
United States | 3 | 7% |
Germany | 1 | 2% |
Brazil | 1 | 2% |
Ireland | 1 | 2% |
Mexico | 1 | 2% |
India | 1 | 2% |
Unknown | 33 | 73% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 14 | 31% |
Student > Ph. D. Student | 7 | 16% |
Student > Master | 5 | 11% |
Professor | 4 | 9% |
Professor > Associate Professor | 3 | 7% |
Other | 7 | 16% |
Unknown | 5 | 11% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 22 | 49% |
Computer Science | 5 | 11% |
Environmental Science | 2 | 4% |
Immunology and Microbiology | 2 | 4% |
Medicine and Dentistry | 2 | 4% |
Other | 4 | 9% |
Unknown | 8 | 18% |