↓ Skip to main content

How has the cost of antiretroviral therapy changed over the years? A database analysis in Italy

Overview of attention for article published in BMC Health Services Research, September 2018
Altmetric Badge

Mentioned by

twitter
1 X user

Citations

dimensions_citation
7 Dimensions

Readers on

mendeley
30 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
How has the cost of antiretroviral therapy changed over the years? A database analysis in Italy
Published in
BMC Health Services Research, September 2018
DOI 10.1186/s12913-018-3507-x
Pubmed ID
Authors

Lucia Taramasso, Federica Demma, Rossella Bitonti, Antonio Ferrazin, Barbara Giannini, Mauro Giacomini, Sabrina Beltramini, Elisabetta Sasso, Claudio Viscoli, Antonio Di Biagio

Abstract

The number of human immunodeficiency virus (HIV)-related hospitalizations has decreased worldwide in recent years, due to the availability of combined antiretroviral therapies (cART). The present analysis aimed to analyse the economic, and clinical burden of HIV management, after the introduction of systematic use of cART. Data from HIV-infected patients, treated at Policlinico San Martino Hospital in Genova (Italy) were retrospectively collected. A comparison between years 2009 and 2015 was performed. HIV-related admissions were identified by using the Diagnosis-Related Group (DRG) codes. The resource consumption of outpatient services was derived by using a modelling approach. Expenditure for drugs was also analysed, as aggregate data. The number of HIV-infected patients was 898 in 2009 and 1006 in 2015. Overall, the virological success rate improved from 2009 to 2015, as the percentage of patients with HIV-RNA < 50 copies/mL increased from 79 to 89% (P < 0.05). The average incidence of hospitalizations per-patient decreased from 0.30 in 2009, to 0.13 in 2015. Average expenditure per-patient decreased from €10,107 in 2009 to €9063 in 2015. The present analysis confirmed the role of cART in controlling HIV viral load and, consequently, in reducing hospitalizations, admissions to day-hospital and the use of outpatient services. Clinical improvements and economic savings more than compensated the investments required to treat HIV-infected patients with cART. Health Authorities should invest in modern cART supply and universal treatment, to use at best the available resources and obtain a cost-effective improvement of health in people living with HIV. Additional research, with the involvement of different centers and the use of patient-specific data, are recommended to consolidate the findings of this analysis.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 30 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 30 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 6 20%
Researcher 4 13%
Student > Ph. D. Student 3 10%
Other 2 7%
Student > Master 2 7%
Other 2 7%
Unknown 11 37%
Readers by discipline Count As %
Nursing and Health Professions 4 13%
Psychology 3 10%
Medicine and Dentistry 3 10%
Economics, Econometrics and Finance 2 7%
Computer Science 1 3%
Other 4 13%
Unknown 13 43%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 September 2018.
All research outputs
#15,544,609
of 23,102,082 outputs
Outputs from BMC Health Services Research
#5,651
of 7,743 outputs
Outputs of similar age
#212,596
of 336,142 outputs
Outputs of similar age from BMC Health Services Research
#143
of 177 outputs
Altmetric has tracked 23,102,082 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,743 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.8. This one is in the 17th percentile – i.e., 17% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 336,142 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 177 others from the same source and published within six weeks on either side of this one. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.