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Vitamin D supplementation to prevent depression and poor physical function in older adults: Study protocol of the D-Vitaal study, a randomized placebo-controlled clinical trial

Overview of attention for article published in BMC Geriatrics, November 2015
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Title
Vitamin D supplementation to prevent depression and poor physical function in older adults: Study protocol of the D-Vitaal study, a randomized placebo-controlled clinical trial
Published in
BMC Geriatrics, November 2015
DOI 10.1186/s12877-015-0148-3
Pubmed ID
Authors

Elisa J. de Koning, Natasja M. van Schoor, Brenda W.J.H. Penninx, Petra J.M. Elders, Annemieke C. Heijboer, Jan. H. Smit, Pierre M. Bet, Maurits W. van Tulder, Martin den Heijer, Harm W.J. van Marwijk, Paul Lips

Abstract

Depressive symptoms and decreased physical functioning are interrelated conditions and common in older persons, causing significant individual and societal burden. Evidence suggests that vitamin D supplementation may be beneficial for both mental and physical functioning. However, previous randomized controlled trials have yielded inconsistent results and often had suboptimal designs. This study examines the effect of vitamin D supplementation on both depressive symptoms and physical functioning in a high-risk population of older persons with low vitamin D status. The D-Vitaal study is a randomized, double-blind, placebo-controlled trial investigating the effects of a daily dose of 1200 IU vitamin D3 versus placebo for one year on depressive symptoms and physical functioning (primary outcomes) in older adults. Participants (N = 155, age 60-80 years) were recruited from the general population. Eligibility criteria included the presence of depressive symptoms, ≥1 functional limitation and serum 25-hydroxyvitamin D levels between 15 and 50/70 nmol/L (depending on season). Secondary outcomes include incidence of major depressive disorder, anxiety symptoms, health-related quality of life, cognitive function and cost-effectiveness of the intervention. With this study, we aim to elucidate the effects of vitamin D supplementation on depressive symptoms and physical functioning in older persons who are at high risk of developing more substantial mental and physical problems. If effective, vitamin D supplementation can be a preventive intervention strategy that is easy to implement in the primary care setting. Netherlands Trial Register NTR3845 . Registered 6 February 2013.

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The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 258 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 <1%
Portugal 1 <1%
Unknown 255 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 48 19%
Student > Bachelor 38 15%
Researcher 24 9%
Student > Ph. D. Student 20 8%
Other 14 5%
Other 45 17%
Unknown 69 27%
Readers by discipline Count As %
Medicine and Dentistry 66 26%
Nursing and Health Professions 35 14%
Psychology 27 10%
Sports and Recreations 12 5%
Agricultural and Biological Sciences 9 3%
Other 29 11%
Unknown 80 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 December 2015.
All research outputs
#13,096,060
of 23,205,257 outputs
Outputs from BMC Geriatrics
#1,922
of 3,287 outputs
Outputs of similar age
#176,619
of 388,347 outputs
Outputs of similar age from BMC Geriatrics
#28
of 50 outputs
Altmetric has tracked 23,205,257 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,287 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.4. This one is in the 40th percentile – i.e., 40% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 388,347 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.
We're also able to compare this research output to 50 others from the same source and published within six weeks on either side of this one. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.