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Coev-web: a web platform designed to simulate and evaluate coevolving positions along a phylogenetic tree

Overview of attention for article published in BMC Bioinformatics, November 2015
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32 Mendeley
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Title
Coev-web: a web platform designed to simulate and evaluate coevolving positions along a phylogenetic tree
Published in
BMC Bioinformatics, November 2015
DOI 10.1186/s12859-015-0785-8
Pubmed ID
Authors

Linda Dib, Xavier Meyer, Panu Artimo, Vassilios Ioannidis, Heinz Stockinger, Nicolas Salamin

Abstract

Available methods to simulate nucleotide or amino acid data typically use Markov models to simulate each position independently. These approaches are not appropriate to assess the performance of combinatorial and probabilistic methods that look for coevolving positions in nucleotide or amino acid sequences. We have developed a web-based platform that gives a user-friendly access to two phylogenetic-based methods implementing the Coev model: the evaluation of coevolving scores and the simulation of coevolving positions. We have also extended the capabilities of the Coev model to allow for the generalization of the alphabet used in the Markov model, which can now analyse both nucleotide and amino acid data sets. The simulation of coevolving positions is novel and builds upon the developments of the Coev model. It allows user to simulate pairs of dependent nucleotide or amino acid positions. The main focus of our paper is the new simulation method we present for coevolving positions. The implementation of this method is embedded within the web platform Coev-web that is freely accessible at http://coev.vital-it.ch/ , and was tested in most modern web browsers.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Finland 1 3%
Canada 1 3%
Unknown 30 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 28%
Researcher 8 25%
Student > Bachelor 4 13%
Student > Master 4 13%
Professor > Associate Professor 3 9%
Other 3 9%
Unknown 1 3%
Readers by discipline Count As %
Agricultural and Biological Sciences 15 47%
Computer Science 6 19%
Biochemistry, Genetics and Molecular Biology 6 19%
Engineering 2 6%
Environmental Science 1 3%
Other 1 3%
Unknown 1 3%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 November 2015.
All research outputs
#13,450,711
of 22,833,393 outputs
Outputs from BMC Bioinformatics
#4,200
of 7,288 outputs
Outputs of similar age
#185,964
of 386,225 outputs
Outputs of similar age from BMC Bioinformatics
#75
of 132 outputs
Altmetric has tracked 22,833,393 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,288 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one is in the 38th percentile – i.e., 38% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 386,225 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.
We're also able to compare this research output to 132 others from the same source and published within six weeks on either side of this one. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.