Title |
Recent progress in understanding the role of ecdysteroids in adult insects: Germline development and circadian clock in the fruit fly Drosophila melanogaster
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Published in |
Zoological Letters, November 2015
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DOI | 10.1186/s40851-015-0031-2 |
Pubmed ID | |
Authors |
Outa Uryu, Tomotsune Ameku, Ryusuke Niwa |
Abstract |
Steroid hormones are one of the major bioactive molecules responsible for the coordinated regulation of biological processes in multicellular organisms. In insects, the principal steroid hormones are ecdysteroids, including 20-hydroxyecdysone. A great deal of research has investigated the roles played by ecdysteroids during insect development, especially the regulatory role in inducing molting and metamorphosis. However, little attention has been paid to the roles of these hormones in post-developmental processes, despite their undisputed presence in the adult insect body. Recently, molecular genetics of the fruit fly Drosophila melanogaster has revealed that ecdysteroid biosynthesis and signaling are indeed active in adult insects, and involved in diverse processes, including oogenesis, stress resistance, longevity, and neuronal activity. In this review, we focus on very recent progress in the understanding of two adult biological events that require ecdysteroid biosynthesis and/or signaling in Drosophila at the molecular level: germline development and the circadian clock. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 1 | <1% |
France | 1 | <1% |
Unknown | 139 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 36 | 26% |
Student > Bachelor | 17 | 12% |
Researcher | 16 | 11% |
Student > Master | 15 | 11% |
Student > Doctoral Student | 12 | 9% |
Other | 19 | 13% |
Unknown | 26 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 51 | 36% |
Agricultural and Biological Sciences | 42 | 30% |
Neuroscience | 6 | 4% |
Environmental Science | 3 | 2% |
Unspecified | 2 | 1% |
Other | 6 | 4% |
Unknown | 31 | 22% |