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Mendeley readers
Attention Score in Context
| Title |
The Role of Nav1.9 Channel in the Development of Neuropathic Orofacial Pain Associated with Trigeminal Neuralgia
|
|---|---|
| Published in |
Molecular Pain, November 2015
|
| DOI | 10.1186/s12990-015-0076-4 |
| Pubmed ID | |
| Authors |
Ana Paula Luiz, Olga Kopach, Sonia Santana-Varela, John N. Wood |
| Abstract |
Trigeminal neuralgia is accompanied by severe mechanical, thermal and chemical hypersensitivity of the orofacial area innervated by neurons of trigeminal ganglion (TG). We examined the role of the voltage-gated sodium channel subtype Nav1.9 in the development of trigeminal neuralgia. We found that Nav1.9 is required for the development of both thermal and mechanical hypersensitivity induced by constriction of the infraorbital nerve (CION). The CION model does not induce change on Nav1.9 mRNA expression in the ipsilateral TG neurons when evaluated 9 days after surgery. These results demonstrate that Nav1.9 channels play a critical role in the development of orofacial neuropathic pain. New routes for the treatment of orofacial neuropathic pain focussing on regulation of the voltage-gated Nav1.9 sodium channel activity should be investigated. |
Mendeley readers
The data shown below were compiled from readership statistics for 58 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 58 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 14 | 24% |
| Student > Master | 11 | 19% |
| Student > Ph. D. Student | 10 | 17% |
| Researcher | 6 | 10% |
| Student > Doctoral Student | 3 | 5% |
| Other | 6 | 10% |
| Unknown | 8 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 17 | 29% |
| Agricultural and Biological Sciences | 10 | 17% |
| Biochemistry, Genetics and Molecular Biology | 6 | 10% |
| Neuroscience | 6 | 10% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 9% |
| Other | 5 | 9% |
| Unknown | 9 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 December 2015.
All research outputs
#16,721,208
of 25,373,627 outputs
Outputs from Molecular Pain
#331
of 669 outputs
Outputs of similar age
#226,920
of 393,173 outputs
Outputs of similar age from Molecular Pain
#3
of 6 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 669 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 393,173 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.