@pop_gen_JED I don't know that it's difficult so much as it's not really possible to move the needle by including recessive effects in an index with plausible economic values, e.g., https://t.co/FyWKuPIeMf. Allele frequency is more important than $$$ value
If you look at Cole (2015; https://t.co/5IcPhLElQe) you'll see that I did essentially the same thing: B_{jk}^{'} = B_{jk} \Sigma_i(P(aa)_i \times v_i), where B_{jk} is parent average less an inbreeding penalty, P(aa) = q_i^2, and v_i is an economic penalty
RT @mrtnj: 17. This is related to mate selection methods for controlling Mendelian deleterious variants by van Eenennaam & Kinghorn (2014)…
17. This is related to mate selection methods for controlling Mendelian deleterious variants by van Eenennaam & Kinghorn (2014) and Cole (2015). https://t.co/9rdbFTlgps https://t.co/6oNGpUXWti