@Grey_Monroe What is your opinion on the view that mutational non-uniform rates are due to genetic structures that evolved through completely random mutations. Check this and you will know what I mean: https://t.co/YD7ff9JPxs
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@halvorz @PowerDNS_Bert Which Duan et al argue is due to GC content changing the rate of curving in the DNA helix https://t.co/yGBTk3Zhih
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Reduced intrinsic DNA curvature leads to increased mutation rate https://t.co/sbqo4gQiAs
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The likelihood of gene #mutation depends on the position on the chromosome that a gene is located: "The shape of the DNA double helix plays a major role in determining the local mutation rate ... likely due to increased exposure to mutagens" https://t.co/r