Title |
Research advances in the relationship between nonalcoholic fatty liver disease and atherosclerosis
|
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Published in |
Lipids in Health and Disease, December 2015
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DOI | 10.1186/s12944-015-0141-z |
Pubmed ID | |
Authors |
Xin Xu, Linlin Lu, Quanyong Dong, Xiaolin Li, Nannan Zhang, Yongning Xin, Shiying Xuan |
Abstract |
Nonalcoholic fatty liver disease (NAFLD) is a metabolic stress-induced liver disease that is closely related not only to genetic susceptibility but also to insulin resistance and highly linked with metabolic syndrome. In recent years, the prevalence of NAFLD has increased rapidly, paralleling the epidemic of type 2 diabetes mellitus and obesity leading to cardiovascular disease. It has been demonstrated that NAFLD is highly associated with atherosclerosis. With recently gained knowledge, it appears that NAFLD may induce insulin resistance, dyslipidemia, oxidative stress, inflammation, and fluctuation of adipokines associated with atherosclerosis. In this review, we aimed to summarize recent discoveries related to both NAFLD and atherosclerosis, and to identify possible mechanisms linking them. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Finland | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Scientists | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Netherlands | 1 | 1% |
Belgium | 1 | 1% |
Unknown | 82 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 15 | 18% |
Student > Bachelor | 13 | 15% |
Researcher | 9 | 11% |
Student > Ph. D. Student | 8 | 10% |
Lecturer | 4 | 5% |
Other | 14 | 17% |
Unknown | 21 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 27 | 32% |
Biochemistry, Genetics and Molecular Biology | 7 | 8% |
Agricultural and Biological Sciences | 7 | 8% |
Nursing and Health Professions | 5 | 6% |
Immunology and Microbiology | 4 | 5% |
Other | 8 | 10% |
Unknown | 26 | 31% |