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Bronchiectasis diagnosed after renal transplantation: a retrospective multicenter study

Overview of attention for article published in BMC Pulmonary Medicine, November 2015
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Title
Bronchiectasis diagnosed after renal transplantation: a retrospective multicenter study
Published in
BMC Pulmonary Medicine, November 2015
DOI 10.1186/s12890-015-0133-9
Pubmed ID
Authors

Sandra Dury, Charlotte Colosio, Isabelle Etienne, Dany Anglicheau, Elodie Merieau, Sophie Caillard, Joseph Rivalan, Eric Thervet, Marie Essig, François Babinet, Jean-François Subra, Olivier Toubas, Philippe Rieu, Claire Launois, Jeanne-Marie Perotin-Collard, François Lebargy, Gaëtan Deslée, on behalf of the Spiesser group

Abstract

Bronchiectasis is characterized by abnormal, permanent and irreversible dilatation of the bronchi, usually responsible for daily symptoms and frequent respiratory complications. Many causes have been identified, but only limited data are available concerning the association between bronchiectasis and renal transplantation. We conducted a retrospective multicenter study of cases of bronchiectasis diagnosed after renal transplantation in 14 renal transplantation departments (French SPIESSER group). Demographic, clinical, laboratory and CT scan data were collected. Forty-six patients were included (mean age 58.2 years, 52.2 % men). Autosomal dominant polycystic kidney disease (32.6 %) was the main underlying renal disease. Chronic cough and sputum (50.0 %) were the major symptoms leading to chest CT scan. Mean duration of symptoms before diagnosis was 1.5 years [0-12.1 years]. Microorganisms were identified in 22 patients, predominantly Haemophilus influenzae. Hypogammaglobulinemia was observed in 46.9 % patients. Bronchiectasis was usually extensive (84.8 %). The total bronchiectasis score was 7.4 ± 5.5 with a significant gradient from apex to bases. Many patients remained symptomatic (43.5 %) and/or presented recurrent respiratory tract infections (37.0 %) during follow-up. Six deaths (13 %) occurred during follow-up, but none were attributable to bronchiectasis. These results highlight that the diagnosis of bronchiectasis should be considered in patients with de novo respiratory symptoms after renal transplantation. Further studies are needed to more clearly understand the mechanisms underlying bronchiectasis in this setting.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 43 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 43 100%

Demographic breakdown

Readers by professional status Count As %
Other 6 14%
Researcher 5 12%
Student > Bachelor 5 12%
Student > Doctoral Student 3 7%
Unspecified 2 5%
Other 9 21%
Unknown 13 30%
Readers by discipline Count As %
Medicine and Dentistry 18 42%
Pharmacology, Toxicology and Pharmaceutical Science 3 7%
Nursing and Health Professions 3 7%
Unspecified 2 5%
Agricultural and Biological Sciences 1 2%
Other 3 7%
Unknown 13 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 December 2015.
All research outputs
#20,297,343
of 22,834,308 outputs
Outputs from BMC Pulmonary Medicine
#1,580
of 1,919 outputs
Outputs of similar age
#239,493
of 285,888 outputs
Outputs of similar age from BMC Pulmonary Medicine
#38
of 48 outputs
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We're also able to compare this research output to 48 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.