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Myeloid-derived suppressor cells in non-neoplastic inflamed organs

Overview of attention for article published in Inflammation and Regeneration, September 2018
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  • Good Attention Score compared to outputs of the same age and source (77th percentile)

Mentioned by

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3 X users

Citations

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39 Dimensions

Readers on

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26 Mendeley
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Title
Myeloid-derived suppressor cells in non-neoplastic inflamed organs
Published in
Inflammation and Regeneration, September 2018
DOI 10.1186/s41232-018-0076-7
Pubmed ID
Authors

Sho Sendo, Jun Saegusa, Akio Morinobu

Abstract

Myeloid-derived suppressor cells (MDSCs) are a highly heterogeneous population of immature myeloid cells with immunosuppressive function. Although their function in tumor-bearing conditions is well studied, less is known about the role of MDSCs in various organs under non-neoplastic inflammatory conditions. MDSCs are divided into two subpopulations, G-MDSCs and M-MDSCs, and their distribution varies between organs. MDSCs negatively control inflammation in inflamed organs such as the lungs, joints, liver, kidneys, intestines, central nervous system (CNS), and eyes by suppressing T cells and myeloid cells. MDSCs also regulate fibrosis in the lungs, liver, and kidneys and help repair CNS injuries. MDSCs in organs are plastic and can differentiate into osteoclasts and tolerogenic dendritic cells according to the microenvironment under non-neoplastic inflammatory conditions. This article summarizes recent findings about MDSCs under inflammatory conditions, especially with respect to their function and differentiation in specific organs.

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X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 26 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 19%
Student > Ph. D. Student 4 15%
Student > Bachelor 2 8%
Student > Doctoral Student 2 8%
Student > Master 2 8%
Other 2 8%
Unknown 9 35%
Readers by discipline Count As %
Immunology and Microbiology 6 23%
Medicine and Dentistry 5 19%
Biochemistry, Genetics and Molecular Biology 3 12%
Agricultural and Biological Sciences 2 8%
Engineering 1 4%
Other 0 0%
Unknown 9 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 January 2019.
All research outputs
#15,745,807
of 25,385,509 outputs
Outputs from Inflammation and Regeneration
#127
of 258 outputs
Outputs of similar age
#195,439
of 350,978 outputs
Outputs of similar age from Inflammation and Regeneration
#2
of 9 outputs
Altmetric has tracked 25,385,509 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 258 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.8. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 350,978 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 7 of them.