@drozcanyucel Faz 3 çalışmaları pekala “noninferiorty” çalışması olarak planlanabilir. Hele elde yararı belli bir ilaç veya aşı varsa faz 3 bu şekilde planlanır. Lütfen faz 3 çalışma çerçevesini aşağıdaki kaynak ve az önce paylaştığım linkten bakar mısınız
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@JeffRouder @MaartenvSmeden @t_mpham Suppose we have a 2x2 factorial trial and one of the treatments is as in the CAP-IT trial. Is 125mg or 250mg the ‘control’, and what are the implications for what we view as ‘main effect’ and ‘interaction’? https://t.co
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@domliebl How would you tackle this statistically? In biomedical research non-inferiority tests are common: https://t.co/0aJQTUVXun but I don't think there's a point in applying them to five observations...