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Optical and material analysis of opacified hydrophilic intraocular lenses after explantation: a laboratory study

Overview of attention for article published in BMC Ophthalmology, November 2015
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Title
Optical and material analysis of opacified hydrophilic intraocular lenses after explantation: a laboratory study
Published in
BMC Ophthalmology, November 2015
DOI 10.1186/s12886-015-0149-1
Pubmed ID
Authors

Tamer Tandogan, Ramin Khoramnia, Chul Young Choi, Alexander Scheuerle, Martin Wenzel, Philipp Hugger, Gerd U. Auffarth

Abstract

The opacification of hydrophilic intraocular lenses (IOLs) is a very rare complication in terms of absolute numbers. We report on the analyses of opacified Euromaxx ALI313Y and ALI313 IOLs (Argonoptics, Germany) using light and scanning electron microscopy, X-ray spectroscopy and optical bench analysis. Opacified Euromaxx ALI313Y and ALI313 IOLs were explanted after patients presented with a decrease in visual acuity. The explants were sent to our laboratory and examined using light and scanning electron microscopy. The composition of the deposits was analysed using X-ray spectroscopy. The optical quality of the intraocular lens (IOL) was assessed using the OptiSpheric IOL PRO optical bench (Trioptics GmbH Wedel, Germany). Modulation transfer function (MTF) was measured at all spatial frequencies and United States Air Force (USAF) 1951 resolution target pictures were documented. Macroscopically, the entire optic was opacified in all IOLs. Light and scanning electron microscopy revealed numerous fine, granular, crystalline-like deposits, which were always distributed in a line parallel to the anterior and posterior surfaces of the IOLs. X-ray spectroscopy could prove the deposits consisted of Calcium and Phosphate. Measurements in the optical bench showed deterioration of MTF values at all spatial frequencies and the USAF target pictures demonstrated a significant reduction of brightness as well as resolution with the opacified IOLs. The calcification of hydrophilic IOLs only occurs rarely. The exact chemical composition of the deposits can be assessed by means of X-ray spectroscopy. Optical quality analysis of the explanted Euromaxx ALI313Y and ALI313 IOLs showed significant reduction of MTF values, which was confirmed by USAF target pictures.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 21 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 24%
Student > Master 4 19%
Student > Ph. D. Student 4 19%
Student > Postgraduate 3 14%
Student > Bachelor 1 5%
Other 3 14%
Unknown 1 5%
Readers by discipline Count As %
Medicine and Dentistry 7 33%
Materials Science 4 19%
Nursing and Health Professions 2 10%
Engineering 2 10%
Physics and Astronomy 1 5%
Other 3 14%
Unknown 2 10%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 December 2015.
All research outputs
#21,264,673
of 23,881,329 outputs
Outputs from BMC Ophthalmology
#2,278
of 2,554 outputs
Outputs of similar age
#332,780
of 392,104 outputs
Outputs of similar age from BMC Ophthalmology
#24
of 35 outputs
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