Title |
EXTUBATE: A randomised controlled trial of nasal biphasic positive airway pressure vs. nasal continuous positive airway pressure following extubation in infants less than 30 weeks' gestation: study protocol for a randomised controlled trial
|
---|---|
Published in |
Trials, December 2011
|
DOI | 10.1186/1745-6215-12-257 |
Pubmed ID | |
Authors |
Suresh Victor, Extubate Trial Group |
Abstract |
Respiratory distress syndrome remains a significant problem among premature infants. Mechanical ventilation through an endotracheal tube remains the mainstay of respiratory support but may be associated with lung injury and the development of chronic lung disease of prematurity. Efforts are needed to reduce the duration of mechanical ventilation in favour of less invasive forms of respiratory support and to improve rates of successful extubation.Non-invasive respiratory support has been demonstrated to be less injurious to the premature lung. Standard practice is to use nasal continuous positive airway pressure (n-CPAP) following extubation to support the baby's breathing. Many clinicians also use nasal biphasic positive airway pressure (n-BiPAP) in efforts to improve rates of successful extubation. However, there is currently no evidence that this confers any advantage over conventional nasal continuous positive airway pressure. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Mexico | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 1% |
Portugal | 1 | 1% |
Unknown | 89 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 15 | 16% |
Researcher | 11 | 12% |
Student > Postgraduate | 8 | 9% |
Other | 7 | 8% |
Student > Master | 7 | 8% |
Other | 20 | 22% |
Unknown | 23 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 45 | 49% |
Nursing and Health Professions | 6 | 7% |
Agricultural and Biological Sciences | 4 | 4% |
Engineering | 2 | 2% |
Neuroscience | 2 | 2% |
Other | 5 | 5% |
Unknown | 27 | 30% |