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Mendeley readers
Attention Score in Context
| Title |
Non-invasive measurement using cardiovascular magnetic resonance of changes in pulmonary artery stiffness with exercise
|
|---|---|
| Published in |
Critical Reviews in Diagnostic Imaging, December 2015
|
| DOI | 10.1186/s12968-015-0213-2 |
| Pubmed ID | |
| Authors |
Omid Forouzan, Jared Warczytowa, Oliver Wieben, Christopher J. François, Naomi C. Chesler |
| Abstract |
Exercise stress tests are commonly used in clinical settings to monitor the functional state of the heart and vasculature. Large artery stiffness is one measure of arterial function that can be quantified noninvasively during exercise stress. Changes in proximal pulmonary artery stiffness are especially relevant to the progression of pulmonary hypertension (PH), since pulmonary artery (PA) stiffness is the best current predictor of mortality from right ventricular failure. Cardiovascular magnetic resonance (CMR) was used to investigate the effect of exercise stress on PA pulse wave velocity (PWV) and relative area change (RAC), which are both non-invasive measures of PA stiffness, in healthy subjects. All 21 subjects (average age 26 ± 4 years; 13 female and 8 male) used a custom-made MR-compatible stepping device to exercise (two stages of mild-to-moderate exercise of 3-4 min duration each) in a supine position within the confines of the scanner. To measure the cross-sectional area and blood flow velocity in the main PA (MPA), two-dimensional phase-contrast (2D-PC) CMR images were acquired. To measure the reproducibility of metrics, CMR images were analyzed by two independent observers. Inter-observer agreements were calculated using the intraclass correlation and Bland-Altman analysis. From rest to the highest level of exercise, cardiac output increased from 5.9 ± 1.4 L/min to 8.2 ± 1.9 L/min (p < 0.05), MPA PWV increased from 1.6 ± 0.5 m/s to 3.6 ± 1.4 m/s (p < 0.05), and MPA RAC decreased from 0.34 ± 0.11 to 0.24 ± 0.1 (p < 0.05). While PWV also increased from the first to second exercise stage (from 2.7 ± 1.0 m/s to 3.6 ± 1.4 m/s, p < 0.05), there was no significant change in RAC between the two exercise stages. We found good inter-observer agreement for quantification of MPA flow, RAC and PWV. These results demonstrate that metrics of MPA stiffness increase in response to acute moderate exercise in healthy subjects and that CMR exercise stress offers great potential in clinical practice to noninvasively assess vascular function. |
X Demographics
The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 36% |
| United Kingdom | 3 | 27% |
| Cyprus | 1 | 9% |
| Unknown | 3 | 27% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 8 | 73% |
| Practitioners (doctors, other healthcare professionals) | 1 | 9% |
| Scientists | 1 | 9% |
| Science communicators (journalists, bloggers, editors) | 1 | 9% |
Mendeley readers
The data shown below were compiled from readership statistics for 66 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 2% |
| Unknown | 65 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 10 | 15% |
| Researcher | 10 | 15% |
| Student > Doctoral Student | 8 | 12% |
| Student > Bachelor | 4 | 6% |
| Other | 4 | 6% |
| Other | 15 | 23% |
| Unknown | 15 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 24 | 36% |
| Engineering | 8 | 12% |
| Psychology | 4 | 6% |
| Biochemistry, Genetics and Molecular Biology | 2 | 3% |
| Sports and Recreations | 2 | 3% |
| Other | 5 | 8% |
| Unknown | 21 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 17. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 February 2016.
All research outputs
#2,231,216
of 25,711,518 outputs
Outputs from Critical Reviews in Diagnostic Imaging
#88
of 1,386 outputs
Outputs of similar age
#35,899
of 397,100 outputs
Outputs of similar age from Critical Reviews in Diagnostic Imaging
#2
of 58 outputs
Altmetric has tracked 25,711,518 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,386 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 397,100 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 58 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.