Title |
Migraine and cluster headache – the common link
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Published in |
The Journal of Headache and Pain, September 2018
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DOI | 10.1186/s10194-018-0909-4 |
Pubmed ID | |
Authors |
Anne Luise Vollesen, Silvia Benemei, Francesca Cortese, Alejandro Labastida-Ramírez, Francesca Marchese, Lanfranco Pellesi, Michele Romoli, Messoud Ashina, Christian Lampl, on behalf of the School of Advanced Studies of the European Headache Federation (EHF-SAS) |
Abstract |
Although clinically distinguishable, migraine and cluster headache share prominent features such as unilateral pain, common pharmacological triggers such glyceryl trinitrate, histamine, calcitonin gene-related peptide (CGRP) and response to triptans and neuromodulation. Recent data also suggest efficacy of anti CGRP monoclonal antibodies in both migraine and cluster headache. While exact mechanisms behind both disorders remain to be fully understood, the trigeminovascular system represents one possible common pathophysiological pathway and network of both disorders. Here, we review past and current literature shedding light on similarities and differences in phenotype, heritability, pathophysiology, imaging findings and treatment options of migraine and cluster headache. A continued focus on their shared pathophysiological pathways may be important in paving future treatment avenues that could benefit both migraine and cluster headache patients. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 3 | 20% |
Brazil | 2 | 13% |
Italy | 2 | 13% |
United States | 1 | 7% |
Canada | 1 | 7% |
Denmark | 1 | 7% |
Spain | 1 | 7% |
Unknown | 4 | 27% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 11 | 73% |
Scientists | 3 | 20% |
Practitioners (doctors, other healthcare professionals) | 1 | 7% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 139 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 25 | 18% |
Student > Ph. D. Student | 16 | 12% |
Student > Master | 16 | 12% |
Other | 15 | 11% |
Researcher | 13 | 9% |
Other | 17 | 12% |
Unknown | 37 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 42 | 30% |
Neuroscience | 17 | 12% |
Nursing and Health Professions | 8 | 6% |
Pharmacology, Toxicology and Pharmaceutical Science | 7 | 5% |
Psychology | 6 | 4% |
Other | 8 | 6% |
Unknown | 51 | 37% |