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Predicting conserved protein motifs with Sub-HMMs

Overview of attention for article published in BMC Bioinformatics, April 2010
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Title
Predicting conserved protein motifs with Sub-HMMs
Published in
BMC Bioinformatics, April 2010
DOI 10.1186/1471-2105-11-205
Pubmed ID
Authors

Kevin Horan, Christian R Shelton, Thomas Girke

Abstract

Profile HMMs (hidden Markov models) provide effective methods for modeling the conserved regions of protein families. A limitation of the resulting domain models is the difficulty to pinpoint their much shorter functional sub-features, such as catalytically relevant sequence motifs in enzymes or ligand binding signatures of receptor proteins.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 5%
United Kingdom 1 3%
Germany 1 3%
Denmark 1 3%
Argentina 1 3%
Unknown 33 85%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 28%
Researcher 9 23%
Student > Master 5 13%
Student > Bachelor 4 10%
Student > Doctoral Student 2 5%
Other 4 10%
Unknown 4 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 23 59%
Biochemistry, Genetics and Molecular Biology 7 18%
Environmental Science 1 3%
Mathematics 1 3%
Computer Science 1 3%
Other 2 5%
Unknown 4 10%