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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Roles of airway smooth muscle dysfunction in chronic obstructive pulmonary disease
|
|---|---|
| Published in |
Journal of Translational Medicine, September 2018
|
| DOI | 10.1186/s12967-018-1635-z |
| Pubmed ID | |
| Authors |
Furong Yan, Hongzhi Gao, Hong Zhao, Madhav Bhatia, Yiming Zeng |
| Abstract |
The airway smooth muscle (ASM) plays an indispensable role in airway structure and function. Dysfunction in ASM plays a central role in the pathogenesis of chronic obstructive pulmonary disease (COPD) and contributes to alterations of contractility, inflammatory response, immunoreaction, phenotype, quantity, and size of airways. ASM makes a key contribution in COPD by various mechanisms including altered contractility and relaxation induce by [Ca2+]i, cell proliferation and hypertrophy, production and modulation of extracellular cytokines, and release of pro-and-anti-inflammatory mediators. Multiple dysfunctions of ASM contribute to modulating airway responses to stimuli, remodeling, and fibrosis, as well as influence the compliance of lungs. The present review highlights regulatory roles of multiple factors in the development of ASM dysfunction in COPD, aims to understand the regulatory mechanism by which ASM dysfunctions are initiated, and explores the clinical significance of ASM on alterations of airway structure and function in COPD and development of novel therapeutic strategies for COPD. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 4 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Science communicators (journalists, bloggers, editors) | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 76 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 76 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 12 | 16% |
| Student > Master | 9 | 12% |
| Student > Bachelor | 8 | 11% |
| Researcher | 5 | 7% |
| Student > Doctoral Student | 4 | 5% |
| Other | 12 | 16% |
| Unknown | 26 | 34% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 11 | 14% |
| Biochemistry, Genetics and Molecular Biology | 9 | 12% |
| Immunology and Microbiology | 8 | 11% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 7% |
| Unspecified | 4 | 5% |
| Other | 12 | 16% |
| Unknown | 27 | 36% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 July 2019.
All research outputs
#15,019,263
of 23,105,443 outputs
Outputs from Journal of Translational Medicine
#2,010
of 4,057 outputs
Outputs of similar age
#202,783
of 341,556 outputs
Outputs of similar age from Journal of Translational Medicine
#24
of 83 outputs
Altmetric has tracked 23,105,443 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,057 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.6. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 341,556 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 83 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.