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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Parturition dysfunction in obesity: time to target the pathobiology
|
|---|---|
| Published in |
Reproductive Biology and Endocrinology, December 2015
|
| DOI | 10.1186/s12958-015-0129-6 |
| Pubmed ID | |
| Authors |
Nicole S. Carlson, Teri L. Hernandez, K. Joseph Hurt |
| Abstract |
Over a third of women of childbearing age in the United States are obese, and during pregnancy they are at increased risk for delayed labor onset and slow labor progress that often results in unplanned cesarean delivery. The biology behind this dysfunctional parturition is not well understood. Studies of obesity-induced changes in parturition physiology may facilitate approaches to optimize labor in obese women. In this review, we summarize known and proposed biologic effects of obesity on labor preparation, contraction/synchronization, and endurance, drawing on both clinical observation and experimental data. We present evidence from human and animal studies of interactions between obesity and parturition signaling in all elements of the birth process, including: delayed cervical ripening, prostaglandin insensitivity, amniotic membrane strengthening, decreased myometrial oxytocin receptor expression, decreased myocyte action potential initiation and contractility, decreased myocyte gap junction formation, and impaired myocyte neutralization of reactive oxygen species. We found convincing clinical data on the effect of obesity on labor initiation and successful delivery, but few studies on the underlying pathobiology. We suggest research opportunities and therapeutic interventions based on plausible biologic mechanisms. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 33% |
| United States | 1 | 17% |
| Unknown | 3 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 161 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Israel | 1 | <1% |
| Brazil | 1 | <1% |
| Unknown | 159 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 24 | 15% |
| Student > Bachelor | 21 | 13% |
| Student > Ph. D. Student | 13 | 8% |
| Researcher | 12 | 7% |
| Other | 11 | 7% |
| Other | 36 | 22% |
| Unknown | 44 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 57 | 35% |
| Nursing and Health Professions | 18 | 11% |
| Agricultural and Biological Sciences | 7 | 4% |
| Engineering | 6 | 4% |
| Biochemistry, Genetics and Molecular Biology | 4 | 2% |
| Other | 16 | 10% |
| Unknown | 53 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 December 2015.
All research outputs
#13,699,949
of 23,940,793 outputs
Outputs from Reproductive Biology and Endocrinology
#438
of 1,042 outputs
Outputs of similar age
#184,393
of 395,023 outputs
Outputs of similar age from Reproductive Biology and Endocrinology
#6
of 11 outputs
Altmetric has tracked 23,940,793 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,042 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one has gotten more attention than average, scoring higher than 57% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 395,023 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.