Title |
PEEP titration during prone positioning for acute respiratory distress syndrome
|
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Published in |
Critical Care, December 2015
|
DOI | 10.1186/s13054-015-1153-9 |
Pubmed ID | |
Authors |
Jeremy R. Beitler, Claude Guérin, Louis Ayzac, Jordi Mancebo, Dina M. Bates, Atul Malhotra, Daniel Talmor |
Abstract |
No major trial evaluating prone positioning for acute respiratory distress syndrome (ARDS) has incorporated a high-positive end-expiratory pressure (high-PEEP) strategy despite complementary physiological rationales. We evaluated generalizability of three recent proning trials to patients receiving a high-PEEP strategy. All trials employed a relatively low-PEEP strategy. After protocol ventilator settings were initiated and the patient was positioned per treatment assignment, post-intervention PEEP was not more than 5 cm H2O in 16.7 % and not more than 10 cm H2O in 66.0 % of patients. Post-intervention PEEP would have been nearly twice the set PEEP had a high-PEEP strategy been employed. Use of either proning or high-PEEP likely improves survival in moderate-severe ARDS; the role for both concomitantly remains unknown. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 9 | 22% |
United Kingdom | 7 | 17% |
Argentina | 4 | 10% |
Costa Rica | 2 | 5% |
Colombia | 1 | 2% |
Greece | 1 | 2% |
Sweden | 1 | 2% |
Malaysia | 1 | 2% |
Italy | 1 | 2% |
Other | 2 | 5% |
Unknown | 12 | 29% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 23 | 56% |
Practitioners (doctors, other healthcare professionals) | 11 | 27% |
Scientists | 5 | 12% |
Science communicators (journalists, bloggers, editors) | 2 | 5% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 1% |
Turkey | 1 | 1% |
Unknown | 93 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Postgraduate | 20 | 21% |
Other | 14 | 15% |
Student > Master | 11 | 12% |
Student > Doctoral Student | 8 | 8% |
Researcher | 7 | 7% |
Other | 21 | 22% |
Unknown | 14 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 61 | 64% |
Nursing and Health Professions | 12 | 13% |
Unspecified | 2 | 2% |
Agricultural and Biological Sciences | 2 | 2% |
Psychology | 1 | 1% |
Other | 3 | 3% |
Unknown | 14 | 15% |