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Human herpesvirus 6A induces apoptosis of primary human fetal astrocytes via both caspase-dependent and -independent pathways

Overview of attention for article published in Virology Journal, December 2011
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2 X users

Citations

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26 Mendeley
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Title
Human herpesvirus 6A induces apoptosis of primary human fetal astrocytes via both caspase-dependent and -independent pathways
Published in
Virology Journal, December 2011
DOI 10.1186/1743-422x-8-530
Pubmed ID
Authors

Bin Gu, Guo-Feng Zhang, Ling-Yun Li, Feng Zhou, Dong-Ju Feng, Chuan-Lin Ding, Jing Chi, Chun Zhang, Dan-Dan Guo, Jing-Feng Wang, Hong Zhou, Kun Yao, Wei-Xing Hu

Abstract

Human herpesvirus 6 (HHV-6) is a T-lymphtropic and neurotropic virus that can infect various types of cells. Sequential studies reported that apoptosis of glia and neurons induced by HHV-6 might act a potential trigger for some central nervous system (CNS) diseases. HHV-6 is involved in the pathogenesis of encephalitis, multiple sclerosis (MS) and fatigue syndrome. However, the mechanisms responsible for the apoptosis of infected CNS cells induced by HHV-6 are poorly understood. In this study, we investigated the cell death processes of primary human fetal astrocytes (PHFAs) during productive HHV-6A infection and the underlying mechanisms.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 26 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 23%
Researcher 5 19%
Professor > Associate Professor 4 15%
Student > Master 4 15%
Student > Bachelor 1 4%
Other 4 15%
Unknown 2 8%
Readers by discipline Count As %
Medicine and Dentistry 5 19%
Biochemistry, Genetics and Molecular Biology 5 19%
Agricultural and Biological Sciences 3 12%
Immunology and Microbiology 3 12%
Chemistry 2 8%
Other 5 19%
Unknown 3 12%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 December 2011.
All research outputs
#14,141,030
of 22,659,164 outputs
Outputs from Virology Journal
#1,594
of 3,024 outputs
Outputs of similar age
#153,992
of 242,260 outputs
Outputs of similar age from Virology Journal
#46
of 103 outputs
Altmetric has tracked 22,659,164 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,024 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.5. This one is in the 42nd percentile – i.e., 42% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 242,260 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 34th percentile – i.e., 34% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 103 others from the same source and published within six weeks on either side of this one. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.