Title |
MRI to assess chemoprevention in transgenic adenocarcinoma of mouse prostate (TRAMP)
|
---|---|
Published in |
BMC Medical Imaging, December 2011
|
DOI | 10.1186/1471-2342-11-21 |
Pubmed ID | |
Authors |
Ali S Arbab, Adarsh Shankar, Nadimpalli RS Varma, Dorrah Deeb, Xiaohua Gao, ASM Iskander, Branislava Janic, Meser M Ali, Subhash C Gautam |
Abstract |
The current method to determine the efficacy of chemoprevention in TRAMP mouse model of carcinoma of prostate (CaP) is by extracting and weighing the prostate at different time points or by immunohistochemistry analysis. Non-invasive determination of volumes of prostate glands and seminal vesicles before, during and after treatment would be valuable in investigating the efficacy of newer chemopreventive agents in CaP. The purpose of this study was to determine whether in vivo magnetic resonance imaging (MRI) using a 3 tesla clinical MRI system can be used to follow the effect of chemoprevention in TRAMP model of mouse CaP. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Canada | 1 | 5% |
Unknown | 19 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 5 | 25% |
Student > Ph. D. Student | 3 | 15% |
Student > Master | 2 | 10% |
Student > Doctoral Student | 1 | 5% |
Other | 1 | 5% |
Other | 2 | 10% |
Unknown | 6 | 30% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 8 | 40% |
Agricultural and Biological Sciences | 3 | 15% |
Biochemistry, Genetics and Molecular Biology | 2 | 10% |
Computer Science | 1 | 5% |
Unknown | 6 | 30% |