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SOX2 expression correlates with lymph-node metastases and distant spread in right-sided colon cancer

Overview of attention for article published in BMC Cancer, December 2011
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Mentioned by

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2 tweeters

Citations

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105 Dimensions

Readers on

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65 Mendeley
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Title
SOX2 expression correlates with lymph-node metastases and distant spread in right-sided colon cancer
Published in
BMC Cancer, December 2011
DOI 10.1186/1471-2407-11-518
Pubmed ID
Authors

Jens Neumann, Fiorina Bahr, David Horst, Lydia Kriegl, Jutta Engel, Raquel Mejías-Luque, Markus Gerhard, Thomas Kirchner, Andreas Jung

Abstract

The transcription factor SOX2, which is involved in the induction of pluripotent stem cells and contributes to colorectal carcinogenesis, is associated with a poor prognosis in colon cancer (CC). Furthermore, SOX2 is a repressor of the transcriptional activity of β-catenin in vitro. Since the majority of CC develop via an activation of the Wnt/β-catenin signalling pathway, indicated by nuclear expression of β-catenin, we wanted to investigate the expression patterns of SOX2 and β-catenin and correlate them with the occurrence of lymph node and distant metastases as indicators of malignant progression.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 2%
China 1 2%
Luxembourg 1 2%
Unknown 62 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 17 26%
Student > Ph. D. Student 14 22%
Student > Master 11 17%
Student > Bachelor 7 11%
Professor > Associate Professor 3 5%
Other 7 11%
Unknown 6 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 21 32%
Medicine and Dentistry 21 32%
Biochemistry, Genetics and Molecular Biology 11 17%
Immunology and Microbiology 2 3%
Environmental Science 1 2%
Other 2 3%
Unknown 7 11%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 December 2011.
All research outputs
#14,338,719
of 21,331,034 outputs
Outputs from BMC Cancer
#3,841
of 7,656 outputs
Outputs of similar age
#163,098
of 249,380 outputs
Outputs of similar age from BMC Cancer
#153
of 293 outputs
Altmetric has tracked 21,331,034 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,656 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 38th percentile – i.e., 38% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 249,380 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 293 others from the same source and published within six weeks on either side of this one. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.