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Dorsal penile nerve block with ropivacaine versus intravenous tramadol for the prevention of catheter-related bladder discomfort: study protocol for a randomized controlled trial

Overview of attention for article published in Trials, December 2015
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Title
Dorsal penile nerve block with ropivacaine versus intravenous tramadol for the prevention of catheter-related bladder discomfort: study protocol for a randomized controlled trial
Published in
Trials, December 2015
DOI 10.1186/s13063-015-1130-2
Pubmed ID
Authors

Jing-yi Li, Ren Liao

Abstract

Catheter-related bladder discomfort (CRBD) is common in male patients under general anesthesia, and it may cause patient agitation and exacerbated postoperative pain. In this study, we will enroll male patients undergoing elective surgery with urinary catheterization after anesthetic induction and compare the efficacy of a dorsal penile nerve block (DPNB) and intravenous tramadol for the prevention of CRBD. This trial is a prospective, open-label, randomized controlled trial that will test the superiority of a dorsal penile nerve block with 0.33 % ropivacaine to the use of intravenous tramadol 1.5 mg/kg for CRBD prevention. A total of 60 male patients undergoing elective surgery with urinary catheterization after anesthetic induction will be randomized to receive either DPNB with 0.33 % ropivacaine (DPNB group) or intravenous tramadol 1.5 mg/kg (TRAM group) after the completion of surgery but before extubation. The primary outcome is the incidence and severity of CRBD. Secondary outcomes include Visual Analog Score (VAS) for postoperative pain, number of patients requiring sulfentanil after operation, acceptance of an indwelling urinary catheter after extraction of the catheter, and postoperative side effects, which include postoperative nausea/vomiting (PONV), vertigo, sedation, drowsiness, and dry mouth. For CRBD prevention, this trial is planned to test the superiority of a dorsal penile nerve block with 0.33 % ropivacaine to the use of intravenous tramadol 1.5 mg/kg. The results will provide new insight into the mechanism of CRBD and new clinical practice for the prevention of CRBD. The registration number is NCT01721031 , which was assigned by the National Institutes of Health Clinical Trials Registry (ClinicalTrials.gov) on 27 October 27.

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Mendeley readers

The data shown below were compiled from readership statistics for 61 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 61 100%

Demographic breakdown

Readers by professional status Count As %
Other 9 15%
Researcher 7 11%
Student > Master 7 11%
Student > Doctoral Student 4 7%
Student > Bachelor 3 5%
Other 10 16%
Unknown 21 34%
Readers by discipline Count As %
Medicine and Dentistry 24 39%
Nursing and Health Professions 3 5%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Immunology and Microbiology 1 2%
Economics, Econometrics and Finance 1 2%
Other 5 8%
Unknown 25 41%