Title |
Detailed genetic analysis of hemagglutinin-neuraminidase glycoprotein gene in human parainfluenza virus type 1 isolates from patients with acute respiratory infection between 2002 and 2009 in Yamagata prefecture, Japan
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Published in |
Virology Journal, December 2011
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DOI | 10.1186/1743-422x-8-533 |
Pubmed ID | |
Authors |
Katsumi Mizuta, Mika Saitoh, Miho Kobayashi, Hiroyuki Tsukagoshi, Yoko Aoki, Tatsuya Ikeda, Chieko Abiko, Noriko Katsushima, Tsutomu Itagaki, Masahiro Noda, Kunihisa Kozawa, Tadayuki Ahiko, Hirokazu Kimura |
Abstract |
Human parainfluenza virus type 1 (HPIV1) causes various acute respiratory infections (ARI). Hemagglutinin-neuraminidase (HN) glycoprotein of HPIV1 is a major antigen. However, the molecular epidemiology and genetic characteristics of such ARI are not exactly known. Recent studies suggested that a phylogenetic analysis tool, namely the maximum likelihood (ML) method, may be applied to estimate the evolutionary time scale of various viruses. Thus, we conducted detailed genetic analyses including homology analysis, phylogenetic analysis (using both the neighbor joining (NJ) and ML methods), and analysis of the pairwise distances of HN gene in HPIV1 isolated from patients with ARI in Yamagata prefecture, Japan. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 1 | 5% |
Unknown | 21 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 6 | 27% |
Student > Bachelor | 3 | 14% |
Student > Master | 3 | 14% |
Researcher | 3 | 14% |
Professor | 1 | 5% |
Other | 2 | 9% |
Unknown | 4 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 6 | 27% |
Biochemistry, Genetics and Molecular Biology | 4 | 18% |
Agricultural and Biological Sciences | 3 | 14% |
Computer Science | 2 | 9% |
Nursing and Health Professions | 1 | 5% |
Other | 2 | 9% |
Unknown | 4 | 18% |