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Advances in mass spectrometry-based clinical biomarker discovery

Overview of attention for article published in Clinical Proteomics, January 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#41 of 285)
  • High Attention Score compared to outputs of the same age (84th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (60th percentile)

Mentioned by

blogs
1 blog
twitter
3 X users

Citations

dimensions_citation
210 Dimensions

Readers on

mendeley
399 Mendeley
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Title
Advances in mass spectrometry-based clinical biomarker discovery
Published in
Clinical Proteomics, January 2016
DOI 10.1186/s12014-015-9102-9
Pubmed ID
Authors

Christopher A. Crutchfield, Stefani N. Thomas, Lori J. Sokoll, Daniel W. Chan

Abstract

The greatest unmet needs in biomarker discovery are those discoveries that lead to the development of clinical diagnostic tests. These clinical diagnostic tests can provide early intervention when a patient would present otherwise healthy (e.g., cancer or cardiovascular disease) and aid clinical decision making with improved clinical outcomes. The past two decades have seen significant technological improvements in the analytical capabilities of mass spectrometers. Mass spectrometers are unique in that they can directly analyze any biological molecule susceptible to ionization. The biological studies of human metabolites and proteins using contemporary mass spectrometry technology (metabolomics and proteomics, respectively) has been ongoing for over a decade. Some of these studies have resulted in exciting insights into human biology. However, relatively few biomarkers have been translated into clinical tests. This review will discuss some key technological developments that have occurred over this time with an emphasis on technologies that will create new avenues for biomarker discovery.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 399 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 <1%
France 1 <1%
Ireland 1 <1%
Italy 1 <1%
United States 1 <1%
Unknown 394 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 77 19%
Researcher 63 16%
Student > Bachelor 51 13%
Student > Master 46 12%
Other 21 5%
Other 71 18%
Unknown 70 18%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 93 23%
Agricultural and Biological Sciences 60 15%
Chemistry 48 12%
Medicine and Dentistry 35 9%
Engineering 16 4%
Other 52 13%
Unknown 95 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 January 2019.
All research outputs
#3,559,559
of 22,837,982 outputs
Outputs from Clinical Proteomics
#41
of 285 outputs
Outputs of similar age
#61,991
of 393,726 outputs
Outputs of similar age from Clinical Proteomics
#2
of 5 outputs
Altmetric has tracked 22,837,982 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 285 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one has done well, scoring higher than 85% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 393,726 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.