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Family-led rehabilitation after stroke in India: the ATTEND trial, study protocol for a randomized controlled trial

Overview of attention for article published in Trials, January 2016
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Title
Family-led rehabilitation after stroke in India: the ATTEND trial, study protocol for a randomized controlled trial
Published in
Trials, January 2016
DOI 10.1186/s13063-015-1129-8
Pubmed ID
Authors

Mohammed Alim, Richard Lindley, Cynthia Felix, Dorcas Beulah Chandramathy Gandhi, Shweta Jain Verma, Deepak Kumar Tugnawat, Anuradha Syrigapu, Craig Stuart Anderson, Ramaprabhu Krishnappa Ramamurthy, Peter Langhorne, Gudlavalleti Venkata Satyanarayana Murthy, Bindiganavale Ramaswamy Shamanna, Maree Lisa Hackett, Pallab Kumar Maulik, Lisa Anne Harvey, Stephen Jan, Hueiming Liu, Marion Walker, Anne Forster, Jeyaraj Durai Pandian

Abstract

Globally, most strokes occur in low- and middle-income countries, such as India, with many affected people having no or limited access to rehabilitation services. Western models of stroke rehabilitation are often unaffordable in many populations but evidence from systematic reviews of stroke unit care and early supported discharge rehabilitation trials suggest that some components might form the basis of affordable interventions in low-resource settings. We describe the background, history and design of the ATTEND trial, a complex intervention centred on family-led stroke rehabilitation in India. The ATTEND trial aims to test the hypothesis that a family-led caregiver-delivered home-based rehabilitation intervention, designed for the Indian context, will reduce the composite poor outcome of death or dependency at 6 months after stroke, in a multicentre, individually randomized controlled trial with blinded outcome assessment, involving 1200 patients across 14 hospital sites in India. The ATTEND trial is testing the effectiveness of a low-cost rehabilitation intervention that could be widely generalizable to other low- and middle-income countries. Clinical Trials Registry-India CTRI/2013/04/003557 . Australian New Zealand Clinical Trials Registry ACTRN12613000078752 . Universal Trial Number U1111-1138-6707.

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Mendeley readers

The data shown below were compiled from readership statistics for 167 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 1 <1%
Unknown 166 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 26 16%
Student > Master 19 11%
Researcher 16 10%
Student > Ph. D. Student 13 8%
Student > Postgraduate 10 6%
Other 40 24%
Unknown 43 26%
Readers by discipline Count As %
Nursing and Health Professions 41 25%
Medicine and Dentistry 34 20%
Unspecified 10 6%
Psychology 9 5%
Neuroscience 7 4%
Other 15 9%
Unknown 51 31%