Title |
Sequencing and characterization of Varicella-Zoster virus vaccine strain SuduVax
|
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Published in |
Virology Journal, December 2011
|
DOI | 10.1186/1743-422x-8-547 |
Pubmed ID | |
Authors |
Jong Ik Kim, Gyoo Seung Jung, Yu Young Kim, Ga Young Ji, Hyung Seok Kim, Wen Dan Wang, Ho Sun Park, Song Yong Park, Geun Hee Kim, Shi Nae Kwon, Keon Myung Lee, Jin Hyun Ahn, Yeup Yoon, Chan Hee Lee |
Abstract |
Varicella-zoster virus (VZV) causes chickenpox in children and shingles in older people. Currently, live attenuated vaccines based on the Oka strain are available worldwide. In Korea, an attenuated VZV vaccine has been developed from a Korean isolate and has been commercially available since 1994. Despite this long history of use, the mechanism for the attenuation of the vaccine strain is still elusive. We attempted to understand the molecular basis of attenuation mechanism by full genome sequencing and comparative genomic analyses of the Korean vaccine strain SuduVax. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 26 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 6 | 23% |
Student > Doctoral Student | 2 | 8% |
Other | 2 | 8% |
Student > Bachelor | 2 | 8% |
Student > Ph. D. Student | 2 | 8% |
Other | 4 | 15% |
Unknown | 8 | 31% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 6 | 23% |
Medicine and Dentistry | 3 | 12% |
Immunology and Microbiology | 3 | 12% |
Biochemistry, Genetics and Molecular Biology | 2 | 8% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 4% |
Other | 2 | 8% |
Unknown | 9 | 35% |