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Title |
Muscle wasting and the temporal gene expression pattern in a novel rat intensive care unit model
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Published in |
BMC Genomics, December 2011
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DOI | 10.1186/1471-2164-12-602 |
Pubmed ID | |
Authors |
Monica Llano-Diez, Ann-Marie Gustafson, Carl Olsson, Hanna Goransson, Lars Larsson |
Abstract |
Acute quadriplegic myopathy (AQM) or critical illness myopathy (CIM) is frequently observed in intensive care unit (ICU) patients. To elucidate duration-dependent effects of the ICU intervention on molecular and functional networks that control the muscle wasting and weakness associated with AQM, a gene expression profile was analyzed at time points varying from 6 hours to 14 days in a unique experimental rat model mimicking ICU conditions, i.e., post-synaptically paralyzed, mechanically ventilated and extensively monitored animals. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
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Geographical breakdown
Country | Count | As % |
---|---|---|
Belgium | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 2% |
Russia | 1 | 2% |
Ireland | 1 | 2% |
Unknown | 52 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 10 | 18% |
Student > Ph. D. Student | 9 | 16% |
Researcher | 8 | 15% |
Student > Bachelor | 7 | 13% |
Professor | 5 | 9% |
Other | 6 | 11% |
Unknown | 10 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 15 | 27% |
Agricultural and Biological Sciences | 12 | 22% |
Biochemistry, Genetics and Molecular Biology | 7 | 13% |
Nursing and Health Professions | 3 | 5% |
Computer Science | 2 | 4% |
Other | 6 | 11% |
Unknown | 10 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 December 2011.
All research outputs
#15,239,825
of 22,659,164 outputs
Outputs from BMC Genomics
#6,657
of 10,610 outputs
Outputs of similar age
#163,367
of 242,398 outputs
Outputs of similar age from BMC Genomics
#177
of 302 outputs
Altmetric has tracked 22,659,164 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 10,610 research outputs from this source. They receive a mean Attention Score of 4.7. This one is in the 29th percentile – i.e., 29% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 242,398 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 302 others from the same source and published within six weeks on either side of this one. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.