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Seasonal variation in haematological and biochemical reference values for healthy young children in The Gambia

Overview of attention for article published in BMC Pediatrics, January 2016
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Title
Seasonal variation in haematological and biochemical reference values for healthy young children in The Gambia
Published in
BMC Pediatrics, January 2016
DOI 10.1186/s12887-016-0545-6
Pubmed ID
Authors

Joseph Okebe, Julia Mwesigwa, Schadrac C. Agbla, Frank Sanya-Isijola, Ismaela Abubakar, Umberto D’Alessandro, Assan Jaye, Kalifa Bojang

Abstract

Haematological and biochemistry reference values for children are important for interpreting clinical and research results however, differences in demography and environment poses a challenge when comparing results. The study defines reference intervals for haematological and biochemistry parameters and examines the effect of seasonality in malaria transmission. Blood samples collected from clinically healthy children, aged 12-59 months, in two surveys during the dry and wet season in the Upper River region of The Gambia were processed and the data analysed to generate reference intervals based on the 2.5(th) and 97.5(th) percentiles of the data. Analysis was based on data from 1141 children with median age of 32 months. The mean values for the total white cell count and differentials; lymphocyte, monocyte and neutrophil decreased with increasing age, were lower in males and higher in the wet season survey. However, platelet values declined with age (p < 0.0001). There was no evidence of effect of gender on mean values of AST, ALT, lymphocytes, monocytes, platelets and haemoglobin. Mean estimates for haematological and biochemistry reference intervals are affected by age and seasonality in the first five years of life. This consistency is important for harmonisation of reference values for clinical care and interpretation of trial results.

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The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 66 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Kenya 1 2%
Unknown 65 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 17%
Student > Ph. D. Student 8 12%
Student > Master 6 9%
Professor 4 6%
Student > Bachelor 4 6%
Other 14 21%
Unknown 19 29%
Readers by discipline Count As %
Medicine and Dentistry 15 23%
Agricultural and Biological Sciences 9 14%
Social Sciences 5 8%
Biochemistry, Genetics and Molecular Biology 4 6%
Nursing and Health Professions 3 5%
Other 11 17%
Unknown 19 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 February 2016.
All research outputs
#15,153,715
of 23,306,612 outputs
Outputs from BMC Pediatrics
#1,968
of 3,084 outputs
Outputs of similar age
#222,469
of 397,404 outputs
Outputs of similar age from BMC Pediatrics
#23
of 37 outputs
Altmetric has tracked 23,306,612 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,084 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.8. This one is in the 32nd percentile – i.e., 32% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 397,404 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 37 others from the same source and published within six weeks on either side of this one. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.