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Mendeley readers
Attention Score in Context
| Title |
On the evolutionary conservation of hydrogen bonds made by buried polar amino acids: the hidden joists, braces and trusses of protein architecture
|
|---|---|
| Published in |
BMC Ecology and Evolution, May 2010
|
| DOI | 10.1186/1471-2148-10-161 |
| Pubmed ID | |
| Authors |
Catherine L Worth, Tom L Blundell |
| Abstract |
The hydrogen bond patterns between mainchain atoms in protein structures not only give rise to regular secondary structures but also satisfy mainchain hydrogen bond potential. However, not all mainchain atoms can be satisfied through hydrogen bond interactions that arise in regular secondary structures; in some locations sidechain-to-mainchain hydrogen bonds are required to provide polar group satisfaction. Buried polar residues that are hydrogen-bonded to mainchain amide atoms tend to be highly conserved within protein families, confirming that mainchain architecture is a critical restraint on the evolution of proteins. We have investigated the stabilizing roles of buried polar sidechains on the backbones of protein structures by performing an analysis of solvent inaccessible residues that are entirely conserved within protein families and superfamilies and hydrogen bonded to an equivalent mainchain atom in each family member. |
Mendeley readers
The data shown below were compiled from readership statistics for 79 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 4% |
| United Kingdom | 1 | 1% |
| Switzerland | 1 | 1% |
| Unknown | 74 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 23 | 29% |
| Researcher | 22 | 28% |
| Student > Master | 12 | 15% |
| Student > Bachelor | 5 | 6% |
| Professor > Associate Professor | 3 | 4% |
| Other | 8 | 10% |
| Unknown | 6 | 8% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 34 | 43% |
| Biochemistry, Genetics and Molecular Biology | 24 | 30% |
| Chemistry | 6 | 8% |
| Physics and Astronomy | 2 | 3% |
| Business, Management and Accounting | 1 | 1% |
| Other | 6 | 8% |
| Unknown | 6 | 8% |
Attention Score in Context
This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 December 2011.
All research outputs
#3,016,617
of 25,374,917 outputs
Outputs from BMC Ecology and Evolution
#793
of 3,714 outputs
Outputs of similar age
#11,590
of 104,958 outputs
Outputs of similar age from BMC Ecology and Evolution
#6
of 50 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,714 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.5. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 104,958 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 50 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.