Title |
Significance of bioinformatics in research of chronic obstructive pulmonary disease
|
---|---|
Published in |
Journal of Clinical Bioinformatics, December 2011
|
DOI | 10.1186/2043-9113-1-35 |
Pubmed ID | |
Authors |
Hong Chen, Xiangdong Wang |
Abstract |
Chronic obstructive pulmonary disease (COPD) is an inflammatory disease characterized by the progressive deterioration of pulmonary function and increasing airway obstruction, with high morality all over the world. The advent of high-throughput omics techniques provided an opportunity to gain insights into disease pathogenesis and process which contribute to the heterogeneity, and find target-specific and disease-specific therapies. As an interdispline, bioinformatics supplied vital information on integrative understanding of COPD. This review focused on application of bioinformatics in COPD study, including biomarkers searching and systems biology. We also presented the requirements and challenges in implementing bioinformatics to COPD research and interpreted these results as clinical physicians. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 1 | 3% |
India | 1 | 3% |
Unknown | 33 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 7 | 20% |
Student > Master | 5 | 14% |
Student > Ph. D. Student | 5 | 14% |
Professor > Associate Professor | 4 | 11% |
Student > Bachelor | 3 | 9% |
Other | 4 | 11% |
Unknown | 7 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 10 | 29% |
Biochemistry, Genetics and Molecular Biology | 5 | 14% |
Medicine and Dentistry | 5 | 14% |
Computer Science | 2 | 6% |
Engineering | 2 | 6% |
Other | 4 | 11% |
Unknown | 7 | 20% |