Higher expression of TNFα-induced genes in the synovium of patients with early rheumatoid arthritis correlates with disease activity, and predicts absence of response to first line therapy

Higher expression of TNFα-induced genes in the synovium of patients with early rheumatoid arthritis correlates with disease activity, and predicts absence of response to first line therapy

Bioportfolio, 20 Jan 2016

Background: IL6-related T cell activation and TNFα-dependent cell proliferation are major targets of therapy in the RA synovium.