@JonathanRueb @GidMK And yet they grade the 2 new RCTs as Moderate quality (page 5). Without High quality RCTs, the door on other lines of evidence ought not be shut. "High quality RCTs with very low risk of bias serve as first level evidence in evidence-
@ID_ethics “A randomised controlled trial (RCT) is the optimal type of experimental design [1] for evaluating causal effect of treatments. ... High quality RCTs with very low risk of bias serve as first level evidence in evidence-based medicine ." https://
RT @gsmaclennan: @jd_wilko ... damn it all to hell, no. rapid review by medic @teadewuyi (I was worried she'd take my job even then) found…
@jd_wilko ... damn it all to hell, no. rapid review by medic @teadewuyi (I was worried she'd take my job even then) found that for even basics like compliance and missing data it was like the Walking Dead https://t.co/jRMEXcwsHL recent reviews show same