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Space GlucoseControl system for blood glucose control in intensive care patients - a European multicentre observational study

Overview of attention for article published in BMC Anesthesiology, January 2016
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Title
Space GlucoseControl system for blood glucose control in intensive care patients - a European multicentre observational study
Published in
BMC Anesthesiology, January 2016
DOI 10.1186/s12871-016-0175-4
Pubmed ID
Authors

Jan Blaha, Barbara Barteczko-Grajek, Pawel Berezowicz, Jiri Charvat, Jiri Chvojka, Teodoro Grau, Jonathan Holmgren, Ulrich Jaschinski, Petr Kopecky, Jan Manak, Mette Moehl, Jonathan Paddle, Marcello Pasculli, Johan Petersson, Sirak Petros, Danilo Radrizzani, Vinodkumar Singh, Joel Starkopf

Abstract

Glycaemia control (GC) remains an important therapeutic goal in critically ill patients. The enhanced Model Predictive Control (eMPC) algorithm, which models the behaviour of blood glucose (BG) and insulin sensitivity in individual ICU patients with variable blood samples, is an effective, clinically proven computer based protocol successfully tested at multiple institutions on medical and surgical patients with different nutritional protocols. eMPC has been integrated into the B.Braun Space GlucoseControl system (SGC), which allows direct data communication between pumps and microprocessor. The present study was undertaken to assess the clinical performance and safety of the SGC for glycaemia control in critically ill patients under routine conditions in different ICU settings and with various nutritional protocols. The study endpoints were the percentage of time the BG was within the target range 4.4 - 8.3 mmol.l(-1), the frequency of hypoglycaemic episodes, adherence to the advice of the SGC and BG measurement intervals. BG was monitored, and insulin was given as a continuous infusion according to the advice of the SGC. Nutritional management (enteral, parenteral or both) was carried out at the discretion of each centre. 17 centres from 9 European countries included a total of 508 patients, the median study time was 2.9 (1.9-6.1) days. The median (IQR) time-in-target was 83.0 (68.7-93.1) % of time with the mean proposed measurement interval 2.0 ± 0.5 hours. 99.6 % of the SGC advices on insulin infusion rate were accepted by the user. Only 4 episodes (0.01 % of all BG measurements) of severe hypoglycaemia <2.2 mmol.l(-1) in 4 patients occurred (0.8 %; 95 % CI 0.02-1.6 %). Under routine conditions and under different nutritional protocols the Space GlucoseControl system with integrated eMPC algorithm has exhibited its suitability for glycaemia control in critically ill patients. ClinicalTrials.gov NCT01523665.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 93 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 93 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 10 11%
Student > Ph. D. Student 8 9%
Student > Master 8 9%
Student > Postgraduate 6 6%
Other 6 6%
Other 15 16%
Unknown 40 43%
Readers by discipline Count As %
Medicine and Dentistry 20 22%
Engineering 14 15%
Nursing and Health Professions 11 12%
Social Sciences 3 3%
Biochemistry, Genetics and Molecular Biology 2 2%
Other 3 3%
Unknown 40 43%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 January 2016.
All research outputs
#20,724,339
of 23,323,574 outputs
Outputs from BMC Anesthesiology
#1,209
of 1,533 outputs
Outputs of similar age
#334,863
of 397,667 outputs
Outputs of similar age from BMC Anesthesiology
#16
of 18 outputs
Altmetric has tracked 23,323,574 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,533 research outputs from this source. They receive a mean Attention Score of 3.2. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 397,667 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.