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A novel inhibitor of fatty acid synthase shows activity against HER2+ breast cancer xenografts and is active in anti-HER2 drug-resistant cell lines

Overview of attention for article published in Breast Cancer Research, December 2011
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (71st percentile)
  • Above-average Attention Score compared to outputs of the same age and source (58th percentile)

Mentioned by

twitter
1 X user
patent
4 patents

Citations

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73 Dimensions

Readers on

mendeley
74 Mendeley
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Title
A novel inhibitor of fatty acid synthase shows activity against HER2+ breast cancer xenografts and is active in anti-HER2 drug-resistant cell lines
Published in
Breast Cancer Research, December 2011
DOI 10.1186/bcr3077
Pubmed ID
Authors

Teresa Puig, Helena Aguilar, Sílvia Cufí, Glòria Oliveras, Carlos Turrado, Sílvia Ortega-Gutiérrez, Bellinda Benhamú, María Luz López-Rodríguez, Ander Urruticoechea, Ramon Colomer

Abstract

Inhibiting the enzyme Fatty Acid Synthase (FASN) leads to apoptosis of breast carcinoma cells, and this is linked to human epidermal growth factor receptor 2 (HER2) signaling pathways in models of simultaneous expression of FASN and HER2.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 74 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Spain 1 1%
United States 1 1%
France 1 1%
Unknown 70 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 15 20%
Student > Ph. D. Student 13 18%
Student > Bachelor 7 9%
Student > Master 6 8%
Professor 5 7%
Other 11 15%
Unknown 17 23%
Readers by discipline Count As %
Agricultural and Biological Sciences 17 23%
Biochemistry, Genetics and Molecular Biology 13 18%
Medicine and Dentistry 12 16%
Chemistry 6 8%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Other 6 8%
Unknown 18 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 April 2023.
All research outputs
#7,960,512
of 25,374,917 outputs
Outputs from Breast Cancer Research
#902
of 2,053 outputs
Outputs of similar age
#66,410
of 248,008 outputs
Outputs of similar age from Breast Cancer Research
#19
of 53 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 2,053 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.2. This one has gotten more attention than average, scoring higher than 54% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 248,008 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 53 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.