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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Early pneumonia and timing of antibiotic therapy in patients after nontraumatic out-of-hospital cardiac arrest
|
|---|---|
| Published in |
Critical Care, February 2016
|
| DOI | 10.1186/s13054-016-1191-y |
| Pubmed ID | |
| Authors |
Kristian Hellenkamp, Sabrina Onimischewski, Jochen Kruppa, Martin Faßhauer, Alexander Becker, Helmut Eiffert, Mark Hünlich, Gerd Hasenfuß, Rolf Wachter |
| Abstract |
While early pneumonia is common in patients after out-of-hospital cardiac arrest (OHCA), little is known about the impact of pneumonia and the optimal timing of antibiotic therapy after OHCA. We conducted a 5-year retrospective cohort study, including patients who suffered from OHCA and were treated with therapeutic hypothermia. ICU treatment was strictly standardized with defined treatment goals and procedures. Medical records, chest radiographic images and microbiological findings were reviewed. Within the study period, 442 patients were admitted to our medical ICU after successfully resuscitated cardiac arrest. Of those, 174 patients fulfilled all inclusion and no exclusion criteria and were included into final analysis. Pneumonia within the first week could be confirmed in 39 patients (22.4 %) and was confirmed or probable in 100 patients (57.5 %), without a difference between survivors and non-survivors (37.8 % vs. 23.1 % confirmed pneumonia, p = 0.125). In patients with confirmed pneumonia a tracheotomy was performed more frequently (28.2 vs. 12.6 %, p = 0.026) compared to patients without confirmed pneumonia. Importantly, patients with confirmed pneumonia had a longer ICU- (14.0 [8.5-20.0] vs. 8.0 [5.0-14.0] days, p < 0.001) and hospital stay (23.0 [11.5-29.0] vs. 15.0 [6.5-25.0] days, p = 0.016). A positive end expiratory pressure (PEEP) > =10.5 mbar on day 1 of the hospital stay was identified as early predictor of confirmed pneumonia (odds ratio 2.898, p = 0.006). No other reliable predictor could be identified. Median time to antibiotic therapy was 8.7 [5.4-22.8] hours, without a difference between patients with or without confirmed pneumonia (p = 0.381) and without a difference between survivors and non-survivors (p = 0.264). Patients receiving antibiotics within 12 hours after admission had a shorter ICU- (8.0 [4.0-14.0] vs. 10.5 [6.0-16.0] vs. 13.5 [8.0-20.0] days, p = 0.004) and hospital-stay (14.0 [6.0-25.0] vs. 16.5 [11.0-27.0] vs. 21.0 [17.0-28.0] days, p = 0.007) compared to patients receiving antibiotics after 12 to 36 or more than 36 hours, respectively. Early pneumonia may extend length of ICU- and hospital-stay after OHCA and its occurrence is difficult to predict. A delayed initiation of antibiotic therapy in OHCA patients may increase the duration of the ICU- and hospital-stay. |
X Demographics
The data shown below were collected from the profiles of 39 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 6 | 15% |
| United States | 4 | 10% |
| Venezuela, Bolivarian Republic of | 2 | 5% |
| Ireland | 2 | 5% |
| Argentina | 1 | 3% |
| Belgium | 1 | 3% |
| Colombia | 1 | 3% |
| India | 1 | 3% |
| Canada | 1 | 3% |
| Other | 6 | 15% |
| Unknown | 14 | 36% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 21 | 54% |
| Practitioners (doctors, other healthcare professionals) | 12 | 31% |
| Science communicators (journalists, bloggers, editors) | 4 | 10% |
| Scientists | 2 | 5% |
Mendeley readers
The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| Denmark | 1 | 2% |
| Unknown | 53 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 7 | 13% |
| Researcher | 7 | 13% |
| Student > Master | 6 | 11% |
| Professor > Associate Professor | 4 | 7% |
| Professor | 3 | 5% |
| Other | 11 | 20% |
| Unknown | 17 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 28 | 51% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 7% |
| Arts and Humanities | 1 | 2% |
| Nursing and Health Professions | 1 | 2% |
| Biochemistry, Genetics and Molecular Biology | 1 | 2% |
| Other | 2 | 4% |
| Unknown | 18 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 29. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 December 2019.
All research outputs
#1,338,983
of 25,374,647 outputs
Outputs from Critical Care
#1,148
of 6,554 outputs
Outputs of similar age
#23,684
of 406,424 outputs
Outputs of similar age from Critical Care
#25
of 84 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,554 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.8. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 406,424 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 84 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.