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Comparison of breast sequential and simultaneous integrated boost using the biologically effective dose volume histogram (BEDVH)

Overview of attention for article published in Radiation Oncology, February 2016
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  • Good Attention Score compared to outputs of the same age (68th percentile)

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6 tweeters


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Readers on

23 Mendeley
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Comparison of breast sequential and simultaneous integrated boost using the biologically effective dose volume histogram (BEDVH)
Published in
Radiation Oncology, February 2016
DOI 10.1186/s13014-016-0590-1
Pubmed ID

Moamen M. O. M. Aly, Yasser Abo-Madyan, Lennart Jahnke, Frederik Wenz, Gerhard Glatting


A method is presented to radiobiologically compare sequential (SEQ) and simultaneously integrated boost (SIB) breast radiotherapy. The method is based on identically prescribed biologically effective dose (iso-BED) which was achieved by different prescribed doses due to different fractionation schemes. It is performed by converting the calculated three-dimensional dose distribution to the corresponding BED distribution taking into consideration the different number of fractions for generic α/β ratios. A cumulative BED volume histogram (BEDVH) is then derived from the BED distribution and is compared for the two delivery schemes. Ten breast cancer patients (4 right-sided and 6 left-sided) were investigated. Two tangential intensity modulated whole breast beams with two other oblique (with different gantry angles) beams for the boost volume were used. The boost and the breast target volumes with either α/β = 10 or 3 Gy, and ipsi-lateral and contra-lateral lungs, heart, and contra-lateral breast as organs at risk (OARs) with α/β = 3 Gy were compared. Based on the BEDVH comparisons, the use of SIB reduced the biological breast mean dose by about 3 %, the ipsi-lateral lung and heart by about 10 %, and contra-lateral breast and lung by about 7 %. BED based comparisons should always be used in comparing plans that have different fraction sizes. SIB schemes are dosimetrically more advantageous than SEQ in breast target volume and OARs for equal prescribed BEDs for breast and boost.

Twitter Demographics

The data shown below were collected from the profiles of 6 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 23 100%

Demographic breakdown

Readers by professional status Count As %
Other 4 17%
Student > Master 4 17%
Researcher 3 13%
Lecturer 2 9%
Student > Bachelor 2 9%
Other 4 17%
Unknown 4 17%
Readers by discipline Count As %
Medicine and Dentistry 8 35%
Physics and Astronomy 6 26%
Nursing and Health Professions 2 9%
Social Sciences 1 4%
Immunology and Microbiology 1 4%
Other 2 9%
Unknown 3 13%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 February 2016.
All research outputs
of 22,418,154 outputs
Outputs from Radiation Oncology
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Outputs of similar age
of 379,891 outputs
Outputs of similar age from Radiation Oncology
of 1 outputs
Altmetric has tracked 22,418,154 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 2,023 research outputs from this source. They receive a mean Attention Score of 2.7. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 379,891 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them