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Antiviral activity of four types of bioflavonoid against dengue virus type-2

Overview of attention for article published in Virology Journal, December 2011
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • High Attention Score compared to outputs of the same age and source (94th percentile)

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14 X users
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1 patent
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2 Facebook pages

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467 Mendeley
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Title
Antiviral activity of four types of bioflavonoid against dengue virus type-2
Published in
Virology Journal, December 2011
DOI 10.1186/1743-422x-8-560
Pubmed ID
Authors

Keivan Zandi, Boon-Teong Teoh, Sing-Sin Sam, Pooi-Fong Wong, Mohd Rais Mustafa, Sazaly AbuBakar

Abstract

Dengue is a major mosquito-borne disease currently with no effective antiviral or vaccine available. Effort to find antivirals for it has focused on bioflavonoids, a plant-derived polyphenolic compounds with many potential health benefits. In the present study, antiviral activity of four types of bioflavonoid against dengue virus type -2 (DENV-2) in Vero cell was evaluated. Anti-dengue activity of these compounds was determined at different stages of DENV-2 infection and replication cycle. DENV replication was measured by Foci Forming Unit Reduction Assay (FFURA) and quantitative RT-PCR. Selectivity Index value (SI) was determined as the ratio of cytotoxic concentration 50 (CC50) to inhibitory concentration 50 (IC50) for each compound.

X Demographics

X Demographics

The data shown below were collected from the profiles of 14 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 467 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 <1%
Switzerland 1 <1%
Indonesia 1 <1%
Italy 1 <1%
Costa Rica 1 <1%
Unknown 462 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 82 18%
Student > Bachelor 73 16%
Student > Ph. D. Student 66 14%
Researcher 45 10%
Student > Doctoral Student 21 4%
Other 53 11%
Unknown 127 27%
Readers by discipline Count As %
Agricultural and Biological Sciences 76 16%
Biochemistry, Genetics and Molecular Biology 63 13%
Chemistry 50 11%
Medicine and Dentistry 41 9%
Pharmacology, Toxicology and Pharmaceutical Science 30 6%
Other 66 14%
Unknown 141 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 April 2023.
All research outputs
#3,066,690
of 25,483,400 outputs
Outputs from Virology Journal
#297
of 3,395 outputs
Outputs of similar age
#22,765
of 249,882 outputs
Outputs of similar age from Virology Journal
#5
of 74 outputs
Altmetric has tracked 25,483,400 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,395 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 24.6. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 249,882 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 74 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 94% of its contemporaries.