↓ Skip to main content

Wheel running from a juvenile age delays onset of specific motor deficits but does not alter protein aggregate density in a mouse model of Huntington's disease

Overview of attention for article published in BMC Neuroscience, April 2008
Altmetric Badge

Mentioned by

f1000
1 research highlight platform

Citations

dimensions_citation
109 Dimensions

Readers on

mendeley
127 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Wheel running from a juvenile age delays onset of specific motor deficits but does not alter protein aggregate density in a mouse model of Huntington's disease
Published in
BMC Neuroscience, April 2008
DOI 10.1186/1471-2202-9-34
Pubmed ID
Authors

Anton van Dellen, Patricia M Cordery, Tara L Spires, Colin Blakemore, Anthony J Hannan

Abstract

Huntington's disease (HD) is a neurodegenerative disorder predominantly affecting the cerebral cortex and striatum. Transgenic mice (R6/1 line), expressing a CAG repeat encoding an expanded polyglutamine tract in the N-terminus of the huntingtin protein, closely model HD. We have previously shown that environmental enrichment of these HD mice delays the onset of motor deficits. Furthermore, wheel running initiated in adulthood ameliorates the rear-paw clasping motor sign, but not an accelerating rotarod deficit.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 127 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 2 2%
United Kingdom 2 2%
United States 2 2%
Italy 1 <1%
Poland 1 <1%
Unknown 119 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 23 18%
Researcher 18 14%
Student > Bachelor 16 13%
Student > Master 11 9%
Professor 9 7%
Other 26 20%
Unknown 24 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 33 26%
Medicine and Dentistry 21 17%
Neuroscience 18 14%
Psychology 11 9%
Biochemistry, Genetics and Molecular Biology 6 5%
Other 12 9%
Unknown 26 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 April 2008.
All research outputs
#15,240,835
of 22,660,862 outputs
Outputs from BMC Neuroscience
#704
of 1,240 outputs
Outputs of similar age
#69,211
of 81,512 outputs
Outputs of similar age from BMC Neuroscience
#6
of 8 outputs
Altmetric has tracked 22,660,862 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,240 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 34th percentile – i.e., 34% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 81,512 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.