Yung-Yang Liu, Cheng-Hung Lee, Rejmon Dedaj, Hang Zhao, Hicham Mrabat, Aviva Sheidlin, Olga Syrkina, Pei-Ming Huang, Hari G Garg, Charles A Hales, Deborah A Quinn
Abstract
Mechanical ventilation with even moderate-sized tidal volumes synergistically increases lung injury in sepsis and has been associated with proinflammatory low-molecular-weight hyaluronan production. High-molecular-weight hyaluronan (HMW HA), in contrast, has been found to be anti-inflammatory. We hypothesized that HMW HA would inhibit lung injury associated with sepsis and mechanical ventilation.
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 April 2009.
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#17,285,668
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#5,468
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#85,842
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Outputs of similar age from Critical Care
#20
of 25 outputs
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