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4-Hydroxynonenal induces apoptosis in human osteoarthritic chondrocytes: the protective role of glutathione-S-transferase

Overview of attention for article published in Arthritis Research & Therapy, September 2008
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (80th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (63rd percentile)

Mentioned by

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2 patents
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1 research highlight platform

Citations

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79 Dimensions

Readers on

mendeley
37 Mendeley
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Title
4-Hydroxynonenal induces apoptosis in human osteoarthritic chondrocytes: the protective role of glutathione-S-transferase
Published in
Arthritis Research & Therapy, September 2008
DOI 10.1186/ar2503
Pubmed ID
Authors

France Vaillancourt, Hassan Fahmi, Qin Shi, Patrick Lavigne, Pierre Ranger, Julio C Fernandes, Mohamed Benderdour

Abstract

4-Hydroxynonenal (HNE) is one of the most abundant and reactive aldehydes of lipid peroxidation products and exerts various effects on intracellular and extracellular signalling cascades. We have previously shown that HNE at low concentrations could be considered as an important mediator of catabolic and inflammatory processes in osteoarthritis (OA). In the present study, we focused on characterizing the signalling cascade induced by high HNE concentration involved in cell death in human OA chondrocytes.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 3%
France 1 3%
Unknown 35 95%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 19%
Student > Ph. D. Student 6 16%
Other 3 8%
Student > Doctoral Student 2 5%
Researcher 2 5%
Other 6 16%
Unknown 11 30%
Readers by discipline Count As %
Agricultural and Biological Sciences 9 24%
Medicine and Dentistry 4 11%
Biochemistry, Genetics and Molecular Biology 4 11%
Chemistry 2 5%
Business, Management and Accounting 1 3%
Other 5 14%
Unknown 12 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 March 2022.
All research outputs
#4,835,823
of 25,374,647 outputs
Outputs from Arthritis Research & Therapy
#1,028
of 3,381 outputs
Outputs of similar age
#17,390
of 98,170 outputs
Outputs of similar age from Arthritis Research & Therapy
#14
of 47 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,381 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 98,170 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 47 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.