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Evaluation of the impact of fibromyalgia in disease activity and treatment effect in spondyloarthritis

Overview of attention for article published in Arthritis Research & Therapy, February 2016
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Citations

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50 Dimensions

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56 Mendeley
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Title
Evaluation of the impact of fibromyalgia in disease activity and treatment effect in spondyloarthritis
Published in
Arthritis Research & Therapy, February 2016
DOI 10.1186/s13075-016-0943-z
Pubmed ID
Authors

Natalia Bello, Adrien Etcheto, Caroline Béal, Maxime Dougados, Anna Moltó

Abstract

Fibromyalgia (FM) can coexist with Spondyloarthritis (SpA) leading to diagnostic and treatment dilemmas, especially in the presence of enthesitis. With this study we aimed to estimate the prevalence of FM in SpA and to compare the clinical/disease features and TNF inhibitors (TNFi) in patients with/without FM. FM was defined by a score = > 5/6 of the Fibromyalgia Rapid Screening Tool (FiRST). SpA patients (according to the rheumatologist) and consecutively consulting in the day care hospital but also in the outpatient clinic at the rheumatology department of a tertiary care university hospital were included. Demographics, disease characteristics, activity and severity and TNFi treatment were compared in patients with and without FM; retention rate of the first TNFi and associated factors were explored (Kaplan Meier and Cox regression). Of the 196 enrolled SpA patients, 42 (21.4 %) were positively screened for FM. No statistically significant differences in the prevalence of FM were found with regard to the fulfillment of the ASAS criteria for peripheral/axial SpA, nor with regard to the fulfillment of the imaging vs. clinical arm of the ASAS criteria. However, patients with coexisting FM presented significantly with more enthesitis, higher disease activity (BASDAI and VAS) and poorer function scores (BASFI). No differences were found with regard to the initiation of TNFi treatment (79.0 % vs. 70.0 %, respectively), but the retention rate of the first TNFi after 2 years was shorter in the group of patients with FM (28.1 % (95 % CI 12.5-44.0) vs. 41.7 % (95 % CI 32.2-51.3), p = 0.01). This study confirms that coexistent FM in SpA might impact the patient-reported outcome indices for disease activity and function, and the retention rate of TNFi treatment.

Twitter Demographics

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Mendeley readers

The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Unknown 55 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 8 14%
Other 6 11%
Student > Bachelor 6 11%
Researcher 5 9%
Student > Ph. D. Student 5 9%
Other 16 29%
Unknown 10 18%
Readers by discipline Count As %
Medicine and Dentistry 26 46%
Nursing and Health Professions 6 11%
Social Sciences 4 7%
Psychology 3 5%
Agricultural and Biological Sciences 2 4%
Other 3 5%
Unknown 12 21%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 February 2018.
All research outputs
#7,580,941
of 12,570,318 outputs
Outputs from Arthritis Research & Therapy
#1,369
of 2,066 outputs
Outputs of similar age
#159,929
of 334,898 outputs
Outputs of similar age from Arthritis Research & Therapy
#1
of 1 outputs
Altmetric has tracked 12,570,318 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,066 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.1. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 334,898 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them