And here comes our previous work on activation of p73 by PpIX which compensates for p53 loss and induces tumor suppression in TP53del cancers. https://t.co/Rf8cGEXgP7
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And here comes the link to our article ⬇️ https://t.co/i0Y4GWsKad
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p73 induces apoptosis in mutant p53 cancers after treatment with standard chemotherapy, investigated or #repurposed drugs and here is our earlier study showing that repurposed PpIX activates p73 and induces apoptosis in mutant p53 cancer cells. https://t.c
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Reactivation of TAp73 tumor suppressor by protoporphyrin IX, a metabolite of aminolevulinic acid, induces apoptosis in TP53-deficient cancer cells https://t.co/Dx90nohaDy https://t.co/8BK6u7kXn9