RT @GenomeMedicine: New - Francica & Rottenberg discuss mechanisms of #PARPi resistance in #cancer and insights into the DNA damage respons…
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'Intriguingly, HR restoration was not observed in BRCA2-deficient tumor cells that acquired PARPi resistance ([9] and unpublished). These data raise the question of whether BRCA1 is less essential than BRCA2 for homology-directed DNA repair.' https://t.co
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New from #ERC_Research https://t.co/MUep46UX75 Mechanisms of PARP inhibitor resistance in cancer and insights into the DNA damage response
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RT @GenomeMedicine: New - Francica & Rottenberg discuss mechanisms of #PARPi resistance in #cancer and insights into the DNA damage respons…