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Efficacy, safety and pharmacokinetic of once-daily boosted saquinavir (1500/100 mg) together with 2 nucleos(t)ide reverse transcriptase inhibitors in real life: a multicentre prospective study

Overview of attention for article published in AIDS Research and Therapy, March 2010
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Title
Efficacy, safety and pharmacokinetic of once-daily boosted saquinavir (1500/100 mg) together with 2 nucleos(t)ide reverse transcriptase inhibitors in real life: a multicentre prospective study
Published in
AIDS Research and Therapy, March 2010
DOI 10.1186/1742-6405-7-5
Pubmed ID
Authors

Luis F López-Cortés, Pompeyo Viciana, Rosa Ruiz-Valderas, Juan Pasquau, Josefa Ruiz, Fernando Lozano, Dolores Merino, Antonio Vergara, Alberto Terrón, Luis González, Antonio Rivero, Agustin Muñoz-Sanz

Abstract

Ritonavir-boosted saquinavir (SQVr) is nowadays regarded as an alternative antiretroviral drug probably due to several drawbacks, such as its high pill burden, twice daily dosing and the requirement of 200 mg ritonavir when given at the current standard 1000/100 mg bid dosing. Several once-daily SQVr dosing schemes have been studied with the 200 mg SQV old formulations, trying to overcome some of these disadvantages. SQV 500 mg strength tablets became available at the end of 2005, thus facilitating a once-daily regimen with fewer pills, although there is very limited experience with this formulation yet.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 2 5%
Brazil 1 3%
Unknown 35 92%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 26%
Librarian 4 11%
Student > Ph. D. Student 4 11%
Student > Bachelor 3 8%
Student > Postgraduate 3 8%
Other 7 18%
Unknown 7 18%
Readers by discipline Count As %
Medicine and Dentistry 20 53%
Computer Science 4 11%
Unspecified 1 3%
Nursing and Health Professions 1 3%
Psychology 1 3%
Other 1 3%
Unknown 10 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 March 2010.
All research outputs
#17,286,379
of 25,374,917 outputs
Outputs from AIDS Research and Therapy
#401
of 637 outputs
Outputs of similar age
#90,994
of 110,204 outputs
Outputs of similar age from AIDS Research and Therapy
#2
of 2 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 637 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.1. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 110,204 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one.