Title |
Isomin: a novel cytoplasmic intermediate filament protein from an arthropod species
|
---|---|
Published in |
BMC Biology, February 2011
|
DOI | 10.1186/1741-7007-9-17 |
Pubmed ID | |
Authors |
Caterina Mencarelli, Silvia Ciolfi, Daniela Caroti, Pietro Lupetti, Romano Dallai |
Abstract |
The expression of intermediate filaments (IFs) is a hallmark feature of metazoan cells. IFs play a central role in cell organization and function, acting mainly as structural stress-absorbing elements. There is growing evidence to suggest that these cytoskeletal elements are also involved in the integration of signalling networks. According to their fundamental functions, IFs show a widespread phylogenetic expression, from simple diblastic animals up to mammals, and their constituent proteins share the same molecular organization in all species so far analysed. Arthropods represent a major exception in this scenario. Only lamins, the nuclear IF proteins, have so far been identified in the model organisms analysed; on this basis, it has been considered that arthropods do not express cytoplasmic IFs. |
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Geographical breakdown
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Demographic breakdown
Readers by professional status | Count | As % |
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Unknown | 98 | 78% |
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Unknown | 97 | 77% |